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. Author manuscript; available in PMC: 2021 Oct 18.
Published in final edited form as: Gastroenterology. 2020 Dec 31;160(5):1784–1798.e0. doi: 10.1053/j.gastro.2020.12.058

Figure 5. Microbiome-related plasma metabolites and liver-transplantation free survival.

Figure 5

(A) The active vitamin B6 metabolite pyridoxal 5’-phosphate (PLP), (B) isoleucine, (C) leucine and (D) valine in plasma of patients with PSC compared to healthy controls. Kaplan-Meier plots showing that low levels (1st quartile) of (E) PLP, (F) isoleucine, (G) leucine and (H) valine were all associated with reduced liver-transplantation free survival in PSC. HC, healthy controls; PLP, pyridoxal 5’-phosphate; PSC, primary sclerosing cholangitis.