Table 1.
Characteristics of patients with current ICD-10 depressive episode and somatic symptoms included in the study (N=84).
| Characteristic | Evidence of inflammation |
Test statistic (P-valuea) | |
|---|---|---|---|
| Yes (hs-CRP ≥3mg/L) |
No (hs-CRP <3mg/L) |
||
| Sample, no. (%) | 40 (48) | 44 (52) | - |
| hs-CRP, mean (SD) | 8.22 (4.95) | 0.92 (0.75) | - |
| hs-CRP, median (IQR) | 7.32 (4.45, 10.64) | 0.66 (0.38, 1.39) | - |
| Age, mean (SD) | 41.30 (11.16) | 35.97 (12.08) | 2.10 (0.04) |
| Female sex, no. (%) | 28 (70) | 32 (73) | 0.08 (0.78) |
| BMI, mean (SD)b | 35.93 (8.07) | 25.62 (6.45) | 7.21 (<0.01)c |
| Ethnicity, no. (%) | |||
| White | 37 (93) | 41 (93) | 0.02 (0.90) |
| Other | 3 (7) | 3 (7) | |
| Relationship status, no. (%) | |||
| Relationship | 24 (60) | 25 (57) | 0.09 (0.77) |
| Single | 16 (40) | 19 (43) | |
| Employment status, no. (%) | |||
| Employed | 32 (80) | 31 (70) | 1.02 (0.31) |
| Unemployed | 8 (20) | 13 (30) | |
| Previous depressive episodes, no. (%) |
|||
| 2 or less | 10 (25) | 11 (25) | 0.02 (1.00) |
| 3 – 4 | 6 (15) | 7 (16) | |
| 5 or more | 16 (40) | 17 (39) | |
| Don’t know | 8 (20) | 9 (20) | |
| Current antidepressant duration, no. of months (SD)b | 20.84 (37.19) | 23.65 (38.26) | 0.34 (0.74) |
| Total past antidepressant medication, no. (%) | |||
| 1 | 18 (45) | 23 (52) | 4.69 (0.10) |
| 2 | 18 (45) | 11 (25) | |
| 3 or more | 4 (10) | 10 (23) | |
| Current antidepressant type, no. (%) |
|||
| SSRI | 25 (62) | 36 (82) | 3.93 (0.04) |
| Other | 15 (38) | 8 (18) | |
| Alcohol use frequency, no. (%) | |||
| Never | 12 (30) | 8 (18) | 2.60 (0.27) |
| Monthly/Yearly | 19 (48) | 20 (46) | |
| More than once per week | 9 (22) | 16 (36) | |
| Tobacco use frequency, no. (%) | |||
| Never | 28 (70) | 26 (59) | 2.21 (0.33) |
| Less than daily | 3 (8) | 8 (18) | |
| Daily | 9 (22) | 10 (23) | |
| Other drug use, no. (%) | 6 (15) | 13 (30) | 2.53 (0.11) |
| Physical comorbidity, no. (%)d | |||
| 0 | 9 (26) | 18 (41) | 2.31 (0.31) |
| 1 | 13 (37) | 15 (34) | |
| 2 or more | 13 (37) | 11 (25) | |
ICD-10, International Classification of Diseases 10th Revision; hs-CRP, high-sensitivity C-reactive protein; SD, standard deviation; IQR, interquartile range; BMI, body mass index; SSRI, selective serotonin reuptake inhibitors.
a
Mean values for continuous variables were compared using independent samples t-test; For categorical variables proportion of participants between groups were compared using Chi-squared test.
b
N=83
c
Variables that violated the assumption of normality (i.e., BMI) were log-transformed before testing significance due to right skew.
d
N=79