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. Author manuscript; available in PMC: 2021 Oct 28.
Published in final edited form as: Annu Rev Microbiol. 2020 Jul 17;74:587–606. doi: 10.1146/annurev-micro-012220-063740

Figure 1. Interactions between signaling variants are composed of two layers: a signaling layer (top) and a response layer (bottom).

Figure 1

The image illustrates the impact of each layer—a signaling bacterium [light orange, also coding for its own receptor (not shown)] can impact the receptor of a different signaling variant [light blue, also coding for its own signal (not shown)]. The responding cell produces a good (green arrows) that can benefit itself or others. Production of goods is costly (red arrows). The right-hand panels illustrate different possible scenarios for interactions at either layer.