Table 1. Biophysical properties of K_ATP channels.

	Kir6.2ΔC	Kir6.2ΔC + SUR1(1-196)	Kir6.2ΔC + SUR1(1-288)	Kir6.2 + SUR1
Po
WT	0.03 ± 0.01 (n = 5)	0.67 ± 0.03 (n = 5)	0.58 ± 0.06 (n = 8)	0.24 ± 0.05 (n = 7)
28Δ32	0.04 ± 0.01 (n = 5)	0.68 ± 0.03 (n = 5)	0.77 ± 0.04 a (n = 8)	0.80 ± 0.03 b (n = 5)
ATP IC50 (μM)
WT	97 ± 2 (n = 7)	330 ± 20 (n = 6)	145 ± 23 (n = 5)	18 ± 2 (n = 6)
28Δ32	162 ± 16 a (n = 7)	365 ± 88 (n = 5)	209 ± 25 (n = 5)	111 ± 37 b (n = 5)

n, Number of oocytes tested. IC₅₀ for Kir6.2ΔC + SUR1^(1-196) and Kir6.2ΔC + SUR1^(1-288) were statistically significantly different from Kir6.2ΔC alone and from each other. There was no significant difference between the Po of Kir6.2ΔC + SUR1^(1-196) and Kir6.2ΔC + SUR1^(1-288), or between the Po of Kir6.2ΔC + SUR1^(1-196) and Kir6.2ΔC 28Δ32 + SUR1^(1-288).

^aP < 0.01 compared to wild-type.

^bP < 0.001 compared to wild-type.