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. Author manuscript; available in PMC: 2021 Nov 1.
Published in final edited form as: Lancet Healthy Longev. 2021 May 21;2(6):e317–e326. doi: 10.1016/S2666-7568(21)00086-6

Figure 3. Univariable and multivariable estimates of genetically elevated apoB, LDL cholesterol and triglycerides with lifespan (A, B) and risk of type 2 diabetes (C, D) using two-sample mendelian randomisation.

Figure 3

Multivariable mendelian randomisation estimates represent the direct effects of each lipoprotein entity, adjusted for the other two traits. ApoB=apolipoprotein B. OR=odds ratio.