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. Author manuscript; available in PMC: 2022 Apr 28.
Published in final edited form as: Nat Genet. 2021 Oct 28;53(11):1527–1533. doi: 10.1038/s41588-021-00945-5

Figure 1. Open Targets Genetics pipeline schematic.

Figure 1

a, Data sources include all available GWAS, as well as variant effect predictions and functional genomic data. b, A number of pipelines are run to perform statistical fine-mapping of GWAS, colocalization with gene expression quantitative trait studies (QTLs) and also between distinct GWAS traits, and integrative “locus-to-gene” prioritization from both genetic and functional genomic input features. c, Outputs of the pipelines are available in a web portal, via programmatic API, and as bulk downloads.