Skip to main content
. Author manuscript; available in PMC: 2021 Dec 8.
Published in final edited form as: FASEB J. 2021 May 1;35(5):e21446. doi: 10.1096/fj.202002705R

Figure 3.

Figure 3

Effect of hypoxic pregnancy and MitoQ on stimulated cardiovascular function in the adult offspring. Values are means ± SEM. for the percent change from baseline in mean arterial pressure (MAP; A), systolic blood pressure (SBP; B), diastolic blood pressure (DBP; C), and the fall in the amplitude of femoral blood flow (FBF Amp; D) in response to in vivo treatment with an intravenous dose of 80 μg kg-1 phenylephrine (PE) in conscious adult offspring of normoxic (N, n = 6-8), hypoxic (H, n = 4-8), hypoxic treated with MitoQ (HM, n = 6-7), or normoxic treated with MitoQ (NM, n = 7) pregnancies. Panels E and F show the reactive hyperemic response in femoral blood flow post-PE infusion in terms of time to peak and the peak amplitude of the femoral dilator response, respectively. Statistical differences are (P < .05): * main effect of hypoxia; † main effect of MitoQ; hypoxia x MitoQ interaction indicated by brackets (Two-Way ANOVA with Tukey’s post hoc comparison)