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. Author manuscript; available in PMC: 2021 Dec 21.
Published in final edited form as: Nat Hum Behav. 2021 Jul 1;5(12):1717–1730. doi: 10.1038/s41562-021-01135-3

Figure 4. Mendelian randomisation of years of education on type 2 diabetes (T2D) and coronary artery disease (CAD) adjusted for age at first birth (AFB) and age at first sex (AFS).

Figure 4

Shows the coefficients and confidence intervals (CIs) of Mendelian Randomisation analyses to examine the effects of SNPs associated with years of education on Type 2 Diabetes (T2D) and Coronary Artery Disease (CAD), after adjustment by AFB and AFS and other covariates. The association with years of education and T2D and CAD are substantially attenuated by the effects of AFB. Even when BMI is included in the model, the level of attenuation of educational attainment by AFB remains striking.