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. Author manuscript; available in PMC: 2022 Jan 5.
Published in final edited form as: Pharm Stat. 2020 Aug 12;20(1):109–116. doi: 10.1002/pst.2059

Table 2. Statistical properties of different correction techniques for a selected number of values for the probability of each treatment being effective.

PPV NPV FWER
K P Uncorrected FWER control FDR control (Corr) Uncorrected FWER control FDR control (Corr) Uncorrected FWER control FDR control (Corr)
3 .05 0.687 0.834 0.833 0.995 0.991 0.990 0.060 0.025 0.025
3 .20 0.912 0.956 0.949 0.976 0.961 0.962 0.052 0.024 0.031
3 .50 0.977 0.986 0.981 0.918 0.886 0.897 0.034 0.022 0.029
3 .80 0.994 0.995 0.994 0.747 0.705 0.728 0.015 0.013 0.015
3 .95 0.999 0.999 0.999 0.392 0.361 0.380 0.004 0.004 0.004
5 .05 0.709 0.884 0.883 0.995 0.988 0.988 0.089 0.026 0.027
5 .20 0.921 0.973 0.961 0.976 0.951 0.955 0.076 0.024 0.038
5 .50 0.977 0.990 0.982 0.922 0.864 0.896 0.052 0.023 0.044
5 .80 0.994 0.996 0.994 0.768 0.695 0.753 0.024 0.017 0.024
5 .95 0.999 0.999 0.999 0.423 0.371 0.416 0.006 0.005 0.006
10 .05 0.747 0.935 0.932 0.995 0.985 0.984 0.140 0.025 0.027
10 .20 0.927 0.984 0.967 0.977 0.937 0.947 0.126 0.026 0.055
10 .50 0.978 0.994 0.981 0.922 0.823 0.890 0.089 0.025 0.076
10 .80 0.994 0.997 0.994 0.788 0.659 0.776 0.043 0.022 0.043
10 .95 0.999 0.999 0.999 0.474 0.378 0.470 0.012 0.010 0.012

Abbreviations: FDR, false-discovery rate; FWER, family-wise error rate; K, number of experimental arms; NPV, negative predictive value; P, probability of each experimental arm being effective; PPV, positive predictive value.