Figure 2. Associations of number of HLA-SE alleles (0/1/2 alleles present) with progression from CSA to inflammatory arthritis.
Corresponding hazard ratios, with 0 HLA-SE alleles as reference category were: (A) HR 1.65 (95% CI 1.06-2.56) and HR 3.03 (1.64-5.61) for 1 and 2 HLA-SE alleles respectively, (B) HR 1.05 (0.52-2.13) and HR 2.32 (1.00-5.41), and (C) HR 1.66 (0.94-2.94) and HR 2.00 (0.76-5.28), see supplementary table 4.
HLA-SE: shared epitope, CSA: clinically suspect arthralgia, ACPA: anti-citrullinated protein antibody, IA: inflammatory arthritis, HR: hazard ratio, CI: confidence interval