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. Author manuscript; available in PMC: 2022 Jan 7.
Published in final edited form as: Ann Rheum Dis. 2021 Jul 20;81(1):48–55. doi: 10.1136/annrheumdis-2021-220546

Table 2. Associations of autoantibodies with development of inflammatory arthritis in patients newly presenting with arthralgia.

Univariable cox regression Multivariable cox regression Multivariable cox regression
CSA cohort HR (95% CI) P-value HR (95% CI) P-value HR (95% CI) P-value
            ACPA IgG 3.29 (2.11-5.13) <0.001 2.55 (1.44-4.53) 0.001 2.97 (1.73-5.10) <0.001
            RF IgM 1.72 (1.11-2.67) 0.015 1.01 (0.61-1.69) 0.96 0.98 (0.58-1.67) 0.95
            AAPA IgG 3.07 (1.90-4.98) <0.001 1.79 (1.02-3.16) 0.043 -- --
            Anti-CarP IgG 2.85 (1.59-5.11) <0.001 -- -- 1.47 (0.75-2.87) 0.26

ACPA: anti-citrullinated protein antibody, RF: rheumatoid factor, AAPA: anti-acetylated protein antibody, anti-CarP: anti-carbamylated protein antibody, HR: hazard ratio, CI: confidence interval