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. Author manuscript; available in PMC: 2022 Apr 1.
Published in final edited form as: Mol Psychiatry. 2020 Jul 14;26(10):5967–5976. doi: 10.1038/s41380-020-0838-x

Figure 2. Age- and sex-adjusted receiver operating characteristic (ROC) curves.

Figure 2

2a Symptomatic mutation carriers versus non-carriers. 2b Presymptomatic mutation carriers within 7 years of expected symptom onset versus non-carriers. Area under the curve (AUC) values are the probability that a randomly selected ’case’ (here, a symptomatic mutation carrier or a presymptomatic carrier within 7 years of expected onset, respectively) is ranked as being at greater risk of being a ’case’ than a randomly selected control of the same age and sex.