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. Author manuscript; available in PMC: 2022 Jan 21.
Published in final edited form as: Nature. 2020 Jul 16;584(7822):635–639. doi: 10.1038/s41586-020-2557-5

Extended Data Figure 5. CpG Methylation analysis of different genomic features and TE families.

Extended Data Figure 5

Analysis of genomic CpG methylation of undifferentiated P14 spermatogonia from (n=3) wildtype, Spocd1 -/- and Miwi2 -/- mice is presented. a, b, Scatter plots comparing CpG methylation levels for the respective genomic features between wildtype and Spocd1-/- or Miwi2-/- (a) and between Spocd1-/- or Miwi2-/- spermatogonia (b) are shown. c, d, Scatter plots comparing CpG methylation levels for the respective TE families between wildtype and Spocd1-/- or Miwi2-/- (c) and between Spocd1-/- or Miwi2-/- spermatogonia (d) are shown. Data is mean from n=3 biological replicates per genotype and shown as individual data points (grey) overlayed by a density map.