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. Author manuscript; available in PMC: 2022 Jan 23.
Published in final edited form as: Lancet Haematol. 2021 Jul 1;8(7):e503–e512. doi: 10.1016/S2352-3026(21)00137-X

Table 1. Characteristics of studies contributing and not contributing data to the main network meta-analysis.

Characteristic Contributed data to the main NMA Did not contribute data to the main NMA
Number of studies 30 23
Total number of women * 3,243 4,854
Publication year (median, min-max) 2014 (1969, 2020) 2005 (1978, 2020)
Country income group n (%)
Low and middle-income countries 22 (73) 14 (61)
Upper-middle and high income countries 8 (27) 9 (39)
Total number of arms 62 47 **
Anaemia status at baseline ***
Mild (109-100 g/L) 11 15
Moderate (99-70 g/L) 44 23
Severe (69-40 g/L) 5 3
Not reported 2 6
Number of unique interventions 15 13
Total number of unique comparisons 19 15
Comparisons
ferrous asparto glycinate vs ferrous ascorbate 1
Carbonyl iron vs ferrous fumarate 1
iron polymaltose complex vs ferrous fumarate 1
Iron chondroitinsulfuric acid complex vs ferrous sulphate 1
Iron amino acid chelate vs ferrous sulphate 1
ferrous gluconate vs ferrous sulphate 1
iron polymaltose complex vs ferrous sulphate 1
NaFeEDTA vs ferrous sulphate 1
lactoferrin vs ferrous sulphate 4 1
ferrous sulphate vs “no-iron intervention” 1 8
IFB vs “no-iron intervention” 1
ferrous gluconate vs “no-iron intervention” 1
NaFeEDTA vs “no-iron intervention” 1
IV iron dextran vs “no-iron intervention” 1
ferrous sulphate vs ferrous sulphate and IV Iron polymaltose complex 1
ferrous sulphate vs IV iron sucrose 7 3
ferrous fumarate vs IV iron sucrose 4
ferrous ascorbate vs IV iron sucrose 2
iron polymaltose complex vs IV iron sucrose 1
ferrous sulphate vs IV iron dextran 1
ferrous gluconate vs IV iron dextran 1
ferrous fumarate vs IV iron dextran 1
lactoferrin vs IV iron dextran 1
ferrous fumarate vs IV iron polymaltose complex 1
ferrous sulphate vs IV ferric carboxymaltose 1
IV iron sucrose vs IV ferric carboxymaltose 2
IV iron sucrose vs IV iron dextran 1 2
ferrous sulphate vs IM iron dextran 2
ferrous sulphate vs IM iron sorbitol citric acid 1
IV iron sucrose vs IM iron sorbitol citric acid 3

NMA, network meta-analysis; IV, intravenous; IM, intramuscular

*

The number of women analysed in eligible arms

**

Arms in two originally 3-arm studies with iron and iron and vitamins vs placebo (Sun 2010, Ma 2010) were combined into one

***

Values correspond to number of arms not studies