Table 2. Associations Between Cardiometabolic Risk Factors and Carotid IMT.
Anthropometry and Other Markers (N=939) | Mean† | SD† | Difference in IMT, mm, per SD Increase of Marker (95% CI)‡ | P Value (difference) |
---|---|---|---|---|
Age, y | 10.8 | 0.4 | 0.0024 (–0.0004 to 0.0052) | 0.10 |
Height, cm | 139.2 | 7.0 | 0.0011 (–0.0011 to 0.0034) | 0.33 |
Weight, kg* | 35.3 | 1.3 | 0.0002 (–0.0020 to 0.0025) | 0.83 |
Ponderal Index, kg/m3 * | 13.1 | 1.2 | –0.0007 (–0.0029 to 0.0015) | 0.54 |
Sum of skinfolds, mm* | 41.7 | 1.6 | –0.0026 (–0.0048 to –0.0004) | 0.02 |
Fat mass index, kg/m5 * | 1.9 | 1.5 | –0.0019 (–0.0041 to 0.0003) | 0.09 |
Systolic BP, mm Hg | 104.4 | 10.6 | 0.0024 (0.0002–0.0046) | 0.03 |
Diastolic BP, mm Hg | 63.2 | 9.0 | 0.0027 (0.0005–0.0048) | 0.01 |
Physical activity CPM§ | 468.9 | 105.2 | 0.0030 (0.0000–0.0061) | 0.05 |
Blood markers (N=831) | ||||
Total cholesterol, mmol/L* | 4.5 | 1.2 | –0.0013 (–0.0036 to 0.0010) | 0.27 |
LDL cholesterol, mmol/L* | 2.6 | 1.3 | –0.0005 (–0.0029 to 0.0019) | 0.67 |
HDL cholesterol, mmol/L | 1.5 | 0.3 | 0.0000 (–0.0024 to 0.0023) | 0.97 |
Triglyceride, mmol/L* | 0.9 | 1.5 | –0.0031 (–0.0055 to -0.0007) | 0.01 |
HbA1c, % | 5.3 | 0.3 | 0.0000 (–0.0024 to 0.0023) | 0.97 |
Glucose, mmol/L | 4.5 | 0.3 | 0.0012 (–0.0011 to 0.0036) | 0.30 |
Insulin, mU/L* | 7.1 | 1.8 | –0.0015 (–0.0039 to 0.0010) | 0.24 |
Insulin resistance* | 0.9 | 1.8 | –0.0010 (–0.0034 to 0.0014) | 0.42 |
C-reactive protein, mg/L* | 0.5 | 3.7 | –0.0015 (–0.0038 to 0.0008) | 0.20 |
IMT indicates intima-media thickness; BP, blood pressure; CPM, counts per minute; LDL, low-density lipoprotein; HDL, high-density lipoprotein.
Log-transformed variable.
Geometric means and geometric SD presented for log-transformed variable.
Difference in IMT for SD (or log SD) for log-transformed variables adjusted for sex, age group, ethnicity, month, and random effect for school.
Analyses based on 728 subjects.