Table 4. Laboratory values before and after acetaminophen and placebo.

	Acetaminophen Baseline	Acetaminophen Week 2	Placebo Baseline	Placebo Week 2
Urea – mmol/L (n=103)	5.6 ± 1.4	5.7 ± 1.6	5.7 ± 1.4	5.6 ± 1.6
Sodium – mmol/L (n=103)	139.8 ± 2.0	139.7 ± 2.5	140.0 ± 1.8	139.9 ± 2.1
Potassium – mmol/L (n=103)	4.3 ± 0.3	4.4 ± 0.4	4.3 ± 0.3	4.4 ± 0.3 †
Creatinine – (μmol/L) (n=103)	77.2 ± 12.0 †	76.3 ± 11.9	77.2 ± 11.9	77.6 ± 12.3
Serum Bicarbonate – mmol/L (n=103)	25.7 ± 2.0	25.4 ± 2.0	25.5 ± 1.9 †	25.6 ± 2.1
Alk Phos – U/L (n=100)	74.2 ± 18.4	70.9 ± 16.2	73.1 ± 16.6	72.2 ± 15.4
ALT – U/L (n=100)	24.3 ± 18.7	36.2 ± 20.7 *	23.5 ± 10.5	22.4 ± 9.6
Bilirubin – μmol/L (n=100)	10.4 ± 4.3	9.8 ± 4.1	10.3 ± 4.8	9.8 ± 4.4

Alk Phos, alkaline phosphatase; ALT, alanine aminotransferase

Data are shown as mean ± SD

^†single data point missing n=102

^*Statistically significant difference (p <0.0001), acetaminophen versus placebo.