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. Author manuscript; available in PMC: 2022 Feb 16.
Published in final edited form as: Vaccine. 2018 Nov 30;37 Suppl 1(Suppl 1):A35–A44. doi: 10.1016/j.vaccine.2018.11.011

Fig. 1. Adapted decision tree framework to estimate burden of human rabies deaths and deaths averted by PEP.

Fig. 1

We considered that some proportion of total bites in the population (expected bites annually, dark red box) are genuine rabies exposures (Bites × prabid = Rabies exposures), and non-exposures ((1 - prabid) × Bites) do not contribute to rabies deaths or averted deaths. Of the genuine rabies exposures, a fraction present to an ARMC and all of these persons receive PEP (Rabies exposures × preport = Reported exposures). Some of these exposed persons would otherwise have become infected and died if they had not received PEP (Reported exposures × pinfect = Deaths averted by PEP). Of the unreported exposures, a proportion will die due to rabies infection (Unreported exposures × pinfect = Deaths due to rabies). (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)