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. Author manuscript; available in PMC: 2022 Sep 1.
Published in final edited form as: Hypertension. 2022 Jan 4;79(3):588–598. doi: 10.1161/HYPERTENSIONAHA.121.18617

Figure 4.

Figure 4

Univariable and multivariable Mendelian randomization estimates for effect of body mass index (BMI), type 2 diabetes (T2DM) and systolic blood pressure (SBP), alone and with adjustment for pre-eclampsia or eclampsia (PET) on the outcome of birthweight of first child for mediation analysis.

Odds ratios and 95% confidence intervals (OR [95% CI]) are presented for every 1-SD increase genetically-predicted BMI and SBP and for every logOR increase in T2DM liability. Adjusted odds ratio (aOR) and 95% CI is presented for every 1-SD increase genetically-predicted SBP adjusted for the effect of every logOR increase in PET risk on birthweight.