Table 1. Characteristics of patients with mutations in syndromic diabetes genes and non-syndromic diabetes genes.
Data is in the format median, (IQR), total for continuous variables, and n/total (%) for categorical variables.
| Characteristic | Patients with mutations in syndromic monogenic diabetes genes | Patients with mutations in non-syndromic monogenic diabetes genes | P |
|---|---|---|---|
| N | 56 | 241 | |
| Age at diagnosis of diabetes (y) | 20 (13.5-29), 56 | 17 (13-25), 241 | 0.09 |
| Diabetes duration (y) | 4 (1-8.5), 56 | 3 (0.5-14), 241 | 0.89 |
| Female | 37 (66%) | 145 (60%) | 0.44 |
| BMI (kg/m2) | 22.0 (20.0-26.9), 49 | 23.7 (21.2-27.6), 197 | 0.05 |
| Extra-pancreatic features | 13 (23%) | 15 (6%) | <0.001 |
| Parent with diabetes | 30 (53%) | 184 (76%) | 0.001 |
| Ethnicity (non-white) | 13 (23%) | 38 (16%) | 0.23 |
| HbA1c (%) | 7.3 (6.5-9.5), 41 | 7 (6.3-8.4), 199 | 0.20 |
| HbA1c (mmol/mol) | 56 (48-80) | 53 (45-68) | 0.20 |
| Insulin treated | 40 (71%) | 95 (39%) | <0.001 |
| Insulin alone | 33 | 73 | |
| Insulin with Oral Hypoglycaemic Drugs | 7 | 22 |