Table 3. Comparison of different gamma activities.
Estimates for movement-related gamma ERS are based on the average of two PD patients performing a joystick task with 345 and 368 repetitions respectively. Estimates for DBS-induced FTG are based on 5 subjects with 3-6 stimulation blocks. If FTG was detected during and after stimulation (2 subjects), estimates of both instances were averaged. Estimates for levodopa-induced FTG are based on 6 PD patients performing a joystick task on dopaminergic medication. Different to movement-related gamma ERS, a narrowband FTG feature was present at rest. Spectrograms were divided into segments of 20-30 s and averaged to cancel out movement effects. Durations correspond to the extent of the contour in Figure 1. Amplitude, frequency and half-prominence width were computed based on the power spectrum of every time point using the findpeaks function and averaged for every subject (see details in Methods). All values are presented as mean [range]. MO: movement onset; ERS: event-related synchronisation.
Movement-relatedgamma ERS | DBS-induced FTG | Levodopa-inducedFTG | |
---|---|---|---|
duration (after MO or DBS stop in sec) | 1.33 [1.27 - 1.39] |
24.98 [7.67 - 53.96] |
n.a. |
amplitude (% change from baseline) | 27.07 [25.51 - 28.64] |
88.94 [44.78 - 198.41] |
n.a. |
frequency (Hz) | 59.54 [58.67 - 60.42] |
78.79 [74.90 - 82.71] |
76.03 [68.15 - 84.55] |
mean peak width (half-prominence in Hz) | 7.89 [7.09 - 8.70] |
4.09 [3.68 - 4.96] |
5.41 [3.90 - 7.24] |