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. Author manuscript; available in PMC: 2022 Feb 28.
Published in final edited form as: Diabetes Care. 2020 Nov 18;44(1):224–230. doi: 10.2337/dc20-1318

Table 3. Multivariable analysis of the relation between quartiles of GIP/GLP-1 and IMTmeanCCA/IMTmaxBulb.

  Quartiles of fasting GIP Quartiles of postchallenge GIP*
β (SE) P β (SE) P
Associations between quartiles of GIP and IMTmeanCCA
  Q1 Referent Referent
  Q2 0.003 (0.010) 0.758 0.020 (0.011) 0.059
  Q3 0.013 (0.011) 0.233 0.012 (0.011) 0.260
  Q4 0.023 (0.011) 0.032 0.015 (0.011) 0.180
  P trend 0.008 (0.003) 0.021 0.004 (0.004) 0.305
Associations between quartiles of GIP and IMTmaxBulb
  Q1 Referent Referent
  Q2 0.023 (0.018) 0.202 −0.010 (0.019) 0.599
  Q3 0.016 (0.018) 0.388 −0.016 (0.020) 0.412
  Q4 0.035 (0.019) 0.065 −0.008 (0.020) 0.683
  P trend 0.010 (0.006) 0.105 0.002 (0.006) 0.761
Associations between quartiles of GLP-1 and IMTmeanCCA
  Q1 Referent Referent
  Q2 0.002 (0.011) 0.828 −0.002 (0.011) 0.878
  Q3 −0.001 (0.011) 0.898 −0.005 (0.011) 0.639
  Q4 −0.007 (0.011) 0.541 −0.018 (0.011) 0.100
  P trend −0.003 (0.004) 0.450 −0.006 (0.006) 0.108
Associations between quartiles of GLP-1 and IMTmaxBulb
  Q1 Referent Referent
  Q2 −0.031 (0.019) 0.115 −0.016 (0.020) 0.430
  Q3 −0.032 (0.019) 0.103 −0.025 (0.019) 0.200
  Q4 −0.038 (0.019) 0.047 −0.041 (0.020) 0.044
  P trend −0.007 (0.006) 0.222 −0.013 (0.006) 0.042

Data are unstandardized β-coefficients (1-SD increase of incretins per mm IMTmeanCCA or IMTmaxBulb) (β) and SEs. Q1, quartile with lowest values; Q4, quartile with highest values. Analyses of fasting incretins are adjusted for age, sex, BMI, SBP, smoking status, diabetes status, FPG, fasting insulin, HDL, triglycerides, AHT, and lipid-lowering treatment (model 2a). Analyses between postchallenge GIP and IMTmeanCCA are adjusted for age, sex, BMI, SBP, smoking status, diabetes status, postchallenge plasma glucose, postchallenge insulin, HDL, triglycerides, AHT, and lipid-lowering treatment (model 2b).

*

2 h postchallenge (at 120 min).