. Author manuscript; available in PMC: 2022 Mar 14.
Published in final edited form as: N Engl J Med. 2022 Mar 10;386(10):911–922. doi: 10.1056/NEJMoa2104535
This Author Accepted Manuscript is licensed for use under the CC-BY-ND license https://creativecommons.org/licenses/by-nd/4.0/