Table 5.
Results of the clinical data uncertainty robustness analysis for the patient case 02-CoA. Estimated model parameter values of the second step of the active mechanics personalisation approach are given. The original values produced by the default initial guesses are listed in the first row and means (M), standard deviations (SD), minima (Min), and maxima (Max) of ten samples are listed in the subsequent rows. Means, standard deviations, minima, and maxima of the relative differences are given in brackets below.
| nTRPN
(-) |
β1
(-) |
nTm
(-) |
[Ca2+]50ref
(μM) |
kUW
(ms−1) |
[Ca2+]res
(μM) |
[Ca2+]max
(μM) |
τCR
(ms) |
τCD
(ms) |
|
|---|---|---|---|---|---|---|---|---|---|
| Original | 3.22 | −1.21 | 5.47 | 0.501 | 0.046 | 0.076 | 0.900 | 164.4 | 149.0 |
| Mean | 3.60 (27.0%) |
−1.20 (0.3%) |
4.94 (11.5%) |
0.507 (1.3%) |
0.055 (32.7%) |
0.075 (1.6%) |
0.900 (<0.1%) |
158.1 (5.4%) |
154.0 (4.8%) |
| SD | 0.94 (16.4%) |
<0.01 (0.2%) |
0.76 (12.4%) |
0.017 (3.3%) |
0.022 (40.4%) |
<0.001 (0.4%) |
<0.001 (<0.1%) |
7.0 (2.1%) |
6.2 (2.4%) |
| Min | 2.42 (9.1%) |
−1.21 (0.0%) |
3.01 (1.8%) |
0.500 (0.1%) |
0.036 (1.1%) |
0.075 (0.8%) |
0.899 (<0.1%) |
147.7 (2.0%) |
141.7 (0.3%) |
| Max | 5.00 (55.1%) |
−1.20 (0.5%) |
5.79 (44.9%) |
0.557 (11.2%) |
0.109 (138.8%) |
0.076 (2.0%) |
0.900 (0.1%) |
173.5 (10.2%) |
162.2 (8.8%) |