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. Author manuscript; available in PMC: 2022 Apr 4.
Published in final edited form as: Dev Psychopathol. 2018 Aug 1;30(3):1145–1156. doi: 10.1017/S0954579418000330

Figure 1. Latent path analytic model: Associations between i-ePGS, cognitive function and internalising and externalising symptoms.

Figure 1

Note. i-ePGS = inflammation-related epigenetic risk score; inverse value of i-ePGS score is depicted in this graph to mirror direction of CRP (higher) based on previous DNAm immune studies (Janusek et al., 2017; Ligthart et al., 2016); only significant pathways shown; Int = internalising symptoms; Ext = externalising symptoms; Cogn Funct = cognitive function; Dep = depression symptoms; Anx = anxiety symptoms; ADHD = attention deficit hyperactivity disorder symptoms; CD = conduct disorder symptoms; ODD = oppositional defiant disorder symptoms;