Boxplots with a) maximum and b) mean values of metabolic ratios in multiple sclerosis lesions, and c) mean values of metabolic ratios in NAWM obtained with different MRSI spatial resolutions; i.e. with 100×100, 64×64, and 32×32 matrix size. Each boxplot contains 77 values.
(***=p<0.001, ns = not significant, NAWM = normal-appearing white matter, tNAA =N-acetylaspartate + N-acetylaspartylglutamate, tCr = creatine + phosphocreatine, tCho = phosphocholine + glycerophosphocholine, mlns = myo-inositol)