FIGURE 2.

Power and expected sample sizes (ESS) under $\mathit{\theta }=(0.5,{\theta }^{(2)})$ and ${\theta }^{(2)}\in \{0,0.1,0.2,0.3,0.4,0.5\}$ for the FSD, 3‐arm 1‐stage ORD (FSD(h)), 3‐arm 2‐stage ORD, and MAMS(m) designs when all designs have the same common total sample size equal to 222 patients. 3‐arm 2‐stage ORD and MAMS(m) use triangular bounds. Results are provided using $10^6$ replications