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. 2022 Jan 19;41(9):1613–1626. doi: 10.1002/sim.9314

TABLE 4.

FWER, maximum sample sizes (Max. SS), expected sample sizes (ESS), and critical bounds under θ=(0,0) for the 3‐arm 2‐stage ORD, 3‐arm 1‐stage ORD (FSD(h)), FSD, and MAMS(m) designs when all designs are powered at 80% to reject both hypotheses under θ=(0.5,0.5)

Design
u1,u2,l1
Max. SS ESS Reject at least one H0k
FSD 1.917, ‐, 1.917 231 231.0 0.05
FSD(h) 1.644, ‐, 1.644 192 192.0 0.05
ORD 1.898, 1.789, 0.633 222 134.4 0.05
MAMS(m) 2.179, 2.055, 0.726 264 166.6 0.05

Note: 3‐arm 2‐stage ORD and MAMS(m) use triangular bounds. Results are provided using 106 replications.