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. Author manuscript; available in PMC: 2022 Apr 29.
Published in final edited form as: OBM Genet. 2021 Oct 29;5(4):15. doi: 10.21926/obm.genet.2104141

Table 1. The association of the medical history of the maternal grandmother with the number of FRAXE repeats.

Condition >21 repeats
N (%)
<22 repeats
N (%)
OR [95% CI] P
N 539 (100) 4117 (100)
Diabetes Type I 8 (1.5) 24 (0.6) 2.40 [1.07, 5.38] 0.033
Diabetes Type II 18 (3.3) 81 (2.1) 1.61 [0.96, 2.70] 0.073
Coronary heart disease 22 (4.1) 112 (2.9) 1.42 [0.89, 2.26] 0.140
A stroke 9 (1.7) 79 (2.1) 0.81 [0.40, 1.63] 0.555
Hypertension 124 (23.0) 783 (20.3) 1.17 [0.94, 1.45] 0.151
Rheumatism 81 (15.0) 529 (13.7) 1.11 [0.86, 1.43] 0.416
Arthritis 132 (24.5) 901 (23.4) 1.06 [0.86, 1.31] 0.573
Chronic bronchitis 13 (2.4) 137 (3.6) 0.67 [0.38, 1.19] 0.173
Breast cancer 20 (3.7) 135 (3.5) 1.06 [0.66, 1.71] 0.808
Other cancer 39 (7.2) 236 (6.1) 1.20 [0.84, 1.70] 0.320
Alcohol problem 14 (2.6) 78 (2.0) 1.29 [0.73, 2.30] 0.386
Schizophrenia 6 (1.1) 9 (0.2) 4.81 [1.70, 13.6] 0.003
Depression 109 (20.2) 790 (20.5) 0.98 [0.79, 1.23] 0.877
Disabled 32 (6.0) 239 (6.3) 0.95 [0.65, 1.39] 0.795