Table 4.

Association between sedentary behaviour at adolescence and elevated psychological distress symptoms (Malaise Inventory) at adolescence (cross-sectional) and adulthood (prospective), using chained multiple imputation for missing values at 34y and 42y (n=4,043).

	Psychological distress (Malaise Inventory)
	16 years		42 years
	22 items	9 items	9 items
	OR (95%CI)	OR (95%CI)	OR (95%CI)
Base model
Mentally-active SB	0.90 (0.62 to 1.32)	0.90 (0.59 to 1.37)	1.01 (0.76 to 1.35)
Mentally-passive SB	1.26 (0.96 to 1.67)	1.01 (0.73 to 1.39)	1.25 (1.02 to 1.53)
Potential mediators at 42 years
Cognition
Mentally-active SB	-	-	1.04 (0.77 to 1.40)
Mentally-passive SB	-	-	1.24 (1.01 to 1.51)
Lifestyle potential mediators
Mentally-active SB	-	-	1.08 (0.81 to 1.45)
Mentally-passive SB	-	-	1.39 (1.11 to 1.74)
Self-rated health
Mentally-active SB	-	-	1.04 (0.77 to 1.39)
Mentally-passive SB	-	-	1.30 (1.04 to 1.63)
Potential Mediators at 34 years
Physical activity
Mentally-active SB	-	-	1.01 (0.76 to 1.35)
Mentally-passive SB	-	-	1.25 (1.02 to 1.53)
Self-rated health
Mentally-active SB	-	-	1.02 (0.76 to 1.37)
Mentally-passive SB	-	-	1.24 (1.01 to 1.52)

Note. Base model: adjusted for sex, other sedentary behaviour pattern (e.g. mentally-active SB adjusting the model of mentally-passive SB) (for 16 years analysis) plus employment status, education, weight status and psychological distress symptoms at 16 years (with 9 items) for 42 years analysis. Cognition model: Base model + vocabulary test (below average vocabulary). Lifestyle potential mediators: Base model + physical activity and TV-viewing during weekdays and weekends. Physical and psychological potential mediators: Base model + self-rated health. OR, odds ratio. 95%CI, 95% confidence interval. SB, sedentary behaviour.