Table 2.
Validation of whole-tract FA correlations, corresponding to Figure 7. Columns show the parameters of the best-fit line y = mx + c and the correlation coefficient, r, between tract FA values from subject-specific fibre bundles and those from each atlas, measured using a repeated measures correlation (Bland and Altman, 1995). Also shown is the difference between the z-transform of the correlation coefficients for the age-specific atlas and the JHU atlas, and the 95% confidence intervals (CI) for this difference. Positive differences indicate a higher correlation with the age-specific atlas. These are shown for the same-site validation data, the HBN data with FOD-based tractography, the HBN data with tensor-based tractography, and the HBN data with minimal processing and tensor-based tractography. *p < 10-10. HBN = Healthy Brain Network; FOD = fibre orientation distribution; JHU = Johns Hopkins University.
Age-specific Atlas | JHU Atlas | Difference between z-transformed correlation coefficients (95% CI) | |||||
---|---|---|---|---|---|---|---|
Dataset | m | c | r | m | c | r | |
Same-site | 0.88 | 0.13 | 0.715* | 0.57 | 0.22 | 0.536* | +=0.298 (+0.115, +0.300) |
HBN (FOD) | 0.84 | 0.15 | 0.781* | 0.59 | 0.25 | 0.617* | +0.328 (+0.231, +0.412) |
HBN (Tensor) | 0.51 | 0.27 | 0.697* | 0.39 | 0.32 | 0.595* | +0.176 (+0.087, +0.281) |
HBN (Minimal) | 0.72 | 0.17 | 0.661* | 0.55 | 0.22 | 0.563* | +0.158 (+0.031, +0.268) |