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. Author manuscript; available in PMC: 2022 Jun 22.
Published in final edited form as: Eur Respir J. 2022 Apr 21;59(4):2100905. doi: 10.1183/13993003.00905-2021

Table 1. Difference in cytokine concentrations between tuberculosis patients who failed treatment (cases) and those who were cured (controls) in the internal validation cohort.

Cytokines Log10 difference in baseline cytokine levels comparing cases to controls
Unadjusted difference (95% CI) p-value Adjusted difference (95% CI) p-value
IL-6 0.29 (0.06 to 0.52) 0.01 0.26 (0.01 to 0.52) 0.04
IFN-γ -0.12 (-0.68 to 0.42) 0.65 -0.38 (-0.98 to 0.21) 0.21
IL-13 0.09 (-0.20 to 0.39) 0.52 0.13 (-0.22 to 0.50) 0.45

Adjusted analysis account for BMI, CXR score including cavitation, smear grade and pre-treatment illness duration. Age and sex are adjusted by study design. CI – confidence interval.