Table 1. ARV treatment guidelines for prevention of mother-to-child transmission of HIV, Cited from Gourlay A et al. (Gourlay et al., 2013).
Option A | Option B | Option B+ | |
---|---|---|---|
Mother (CD45350 cells/mm3) | Triple ARVs, starting from diagnosis and continued for life | Triple ARVs, starting from diagnosis and continued for life | Triple ARVs regardless of CD4 count, starting from diagnosis and continued for life |
Mother (CD4350 cells/mm3) | Prophylaxis: Antepartum: AZT from 14 weeks gestation Intrapartum: sd NVP at onset of labour and AZT/3TC Postpartum: AZT/3TC for seven days | Prophylaxis: Triple ARVs from 14 weeks gestation until one week after exposure to breastmilk has ended | |
Infant | NVP (daily) from birth until one week after cessation of breastfeeding, or until age four to six weeks if replacement feeding | NVP or AZT (daily) from birth until age four to six weeks (regardless of infant feeding method) | NVP or AZT (daily) from birth until age four to six weeks (regardless of infant feeding method) |
Note: ARV: antiretroviral; AZT: azidothymidine; NVP: nevirapine; sd: single-dose.