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. Author manuscript; available in PMC: 2022 Jun 28.
Published in final edited form as: Glob Public Health. 2020 Dec 4;16(2):227–240. doi: 10.1080/17441692.2020.1851386

Table 1. ARV treatment guidelines for prevention of mother-to-child transmission of HIV, Cited from Gourlay A et al. (Gourlay et al., 2013).

Option A Option B Option B+
Mother (CD45350 cells/mm3) Triple ARVs, starting from diagnosis and continued for life Triple ARVs, starting from diagnosis and continued for life Triple ARVs regardless of CD4 count, starting from diagnosis and continued for life
Mother (CD4350 cells/mm3) Prophylaxis: Antepartum: AZT from 14 weeks gestation Intrapartum: sd NVP at onset of labour and AZT/3TC Postpartum: AZT/3TC for seven days Prophylaxis: Triple ARVs from 14 weeks gestation until one week after exposure to breastmilk has ended
Infant NVP (daily) from birth until one week after cessation of breastfeeding, or until age four to six weeks if replacement feeding NVP or AZT (daily) from birth until age four to six weeks (regardless of infant feeding method) NVP or AZT (daily) from birth until age four to six weeks (regardless of infant feeding method)

Note: ARV: antiretroviral; AZT: azidothymidine; NVP: nevirapine; sd: single-dose.