Skip to main content
. Author manuscript; available in PMC: 2022 Jun 28.
Published in final edited form as: Mov Disord. 2021 Aug 5;36(12):2811–2820. doi: 10.1002/mds.28727

Table 3. Adjusted mortality rates by age group, gender calendar year, social deprivation, and smoking.

Variable PD cohort Non-PD cohort
Events Person-years (1000) aAdjusted mortality rate (95% CI) P value Events Person-years (1000) aAdjusted mortality rate (95% CI) P value Mortality rate ratio bP value cP value
Age group, y
   50–59   14   2.09     6.98 (3.0 to 10.97) <0.001     51   10.63 4.46 (3.30 to 5.62)   <0.001 1.48 (0.80 to 2.76)   0.212 0.474
   60–69   107   7.74   14.20 (11.30 to 17.09)   521   38.41 13.04 (11.81 to 14.27) 1.08 (0.87 to 1.33)   0.497
   70–79   571 14.95   39.57 (35.98 to 43.16) 2537   74.70 33.53 (31.90 to 35.16) 1.17 (1.07 to 1.28)   0.001
   80–89 1052 10.34 105.75 (98.78 to 112.71) 4813   53.35 92.91 (89.23 to 96.59) 1.14 (1.07 to 1.22) <0.001
   >90   287   1.09 285.69 (250.05 to 321.32) 1245     5.97   223.98 (209.40 to 238.55) 1.28 (1.12 to 1.45) <0.001
Gender
   Male 1288 21.65   65.99 (61.77 to 70.20) <0.001 5792 109.53 54.76 (52.41 to 57.12) <0.001 1.18 (1.11 to 1.25) <0.001 0.452
   Female   743 14.58   51.82 (47.48 to 56.17) 3375   73.39 44.71 (42.67 to 46.74) 1.14 (1.06 to 1.23)   0.001
Townsend quintile
   1 (least deprived)   510 10.37   55.65 (50.21 to 61.09)   0.0197 1939   47.19 44.25 (41.53 to 46.98) <0.001 1.24 (1.13 to 1.37) <0.001 0.323
   2   482   8.54   58.85 (53.02 to 64.68) 2023   41.57 48.77 (45.90 to 51.64) 1.19 (1.08 to 1.32)   0.001
   3   404   6.69   66.03 (59.30 to 72.75) 1919   35.70 53.56 (50.29 to 56.83) 1.19 (1.08 to 1.32)   0.001
   4   291   5.05   61.08 (53.75 to 68.40) 1630   27.52 56.51 (52.48 to 60.54) 1.04 (0.92 to 1.18)   0.497
   5 (most deprived)   210   3.0   67.88 (57.89 to 77.87) 1049   17.67 59.36 (54.55 to 64.17) 1.09 (0.94 to 1.26)   0.246
   Missing data   134   607
Smoking status
   Non-smoker 1035 20.40   53.87 (50.24 to 57.50) <0.001 3649   82.57 44.21 (42.10 to 46.32) <0.001 1.18 (1.11 to 1.26) <0.001 0.086
   Ex-smoker   716 10.76   65.14 (59.85 to 70.43) 3450   60.03 54.02 (51.62 to 56.43) 1.19 (1.10 to 1.28) <0.001
   Current smoker   149   2.50   74.24 (61.70 to 86.78) 1378   23.88 74.74 (69.82 to 79.66) 0.96 (0.80 to 1.13)   0.604
   Missing data   131   690

Abbreviations: PD, Parkinson’s disease; CI, confidence interval, y, years.

a

Adjusted for age, gender calendar year, social deprivation, and smoking.

b

Wald test for categorical variable.

c

Wald test for multiplicative interaction.