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. 2022 Apr 10;28(13):2911–2922. doi: 10.1158/1078-0432.CCR-21-1643

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©2022 The Authors; Published by the American Association for Cancer Research

This open access article is distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) license.

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Figure 3. Focal gene amplifications and deletions in early-stage and late-stage cohorts. A, Purity comparison of early-stage and late-stage cohorts. B, Ploidy comparison of early-stage and late-stage cohorts; Mann–Whitney test. C, Global CN amplifications, gains and losses in early-stage and late-stage cohorts. D, Estimation of focal amplifications and deletions in 17 genes of interest, determined by sWGS. The top plot shows the number of amplifications and deletions in each tumor sample. — Focal gene amplifications and deletions in early-stage and late-stage cohorts. A, Purity comparison of early-stage and late-stage cohorts. B, Ploidy comparison of early-stage and late-stage cohorts; Mann–Whitney test. C, Global CN amplifications, gains and losses in early-stage and late-stage cohorts. D, Estimation of focal amplifications and deletions in 17 genes of interest, determined by sWGS. The top plot shows the number of amplifications and deletions in each tumor sample.