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. Author manuscript; available in PMC: 2022 Jul 5.
Published in final edited form as: Nat Med. 2021 Apr 9;27(4):668–676. doi: 10.1038/s41591-021-01310-z

Figure 4. Regional association plots of the IFNAR2-IL10RB locus.

Figure 4

Regional association plots for a, IL10RB gene expression in tibial nerve tissue from GTEx (N=532), b, COVID-19 hospitalization from HGI and MVP trans-ancestry meta-analysis (N=1,377,758) c, d, Vascular endothelial growth factor receptor 2 (VEGFR2) and tryptase gamma (TPSG1), respectively, measured by SomaLogic in 3,301 INTERVAL participants. All show the correlation (1000G European ancestry) for rs13050728, the cis-eQTL most associated with COVID-19 hospitalization in the IL10RB-IFNAR2 region. All colocalize with each other (PP.H4>0.96 for all).