Table 1. PAA-OH and PAA-RGD Hydrogel formulations and elastic modulus measurements.
| 1AA wt% | 2BA wt% | PAA-OH Hydrogel | 3Elastic modulus PAA-OH | PAA-RGD Hydrogel | 3Elastic modulus PAA-RGD |
|---|---|---|---|---|---|
| 3.5 | 0.03 | PAA-OH1 | 0.32 ± 0.03 | PAA-RGD1 | 2.79 ± 0.38 |
| 3 | 0.15 | PAA-OH2 | 3.15 ± 0.27 | PAA-RGD2 | 4.86 ± 1.02 |
| 5 | 0.15 | PAA-OH3 | 6.09 ± 1.35 | PAA-RGD3 | 13.81 ± 1.52 |
| 5 | 0.225 | PAA-OH4 | 13.39 ± 1.73 | PAA-RGD4 | 21.07 ± 3.41 |
| 8 | 0.48 | PAA-OH5 | 50.01 ± 3.07 | PAA-RGD5 | 57.48 ±4.00 |
1
AA represent the sum of the monofunctional acrylates Acrylamide and N-hydroxyethyl acrylamide (HEA) for PAA-OH gels, and Acrylamide alone for PAA-RGD gels. The amount of HEA is fixed at 0.1M. A fixed amount of ACR-PEG-MAL-RGD of 3mM has been added to the composition.
2
BA wt% is the weight percent of bisacrylamide
3
Stiffness measurements by micropipette aspiration.[40] The data indicate that the effect of the maleimide-modified acrylate addition is to increase gel stiffnesses.