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. Author manuscript; available in PMC: 2022 Jul 17.
Published in final edited form as: J Hepatol. 2018 Sep 8;70(1):40–49. doi: 10.1016/j.jhep.2018.08.021

Fig. 5. Impaired Gd-DTPA clearance in the prefrontal cortex, evaluated by SF-ICP-MS in plasma, CSF and brain tissue of animals with HE.

Fig. 5

Summary data illustrating Gd concentration in the (A) plasma, (B) CSF and (C) frontal, middle and hind brain tissue of sham-operated (n = 6) and BDL (n = 6) animals. Statistical comparisons for CSF and plasma samples were performed using a Student’s t test while statistical comparisons of brain data were performed using 2-way ANOVA followed by Bonferroni post hoc test. p values indicate the level of differences between the sham-operated and BDL groups. BDL, bile duct ligation; CSF, cerebrospinal fluid; HE, hepatic encephalopathy.