Extended Data Fig. 2. Phylogenetic tree of selected terpene cyclase β domains.

Maximum-likelihood tree of β domains from functionally characterized and unknown terpene cyclases, as described in the Materials and Methods above. Organisms are colored according to the phylogeny of their origin: Protists grey, animals gold, fungi red, plants green, and bacteria blue. Terpene enzyme class, domain architecture, and product are also indicated.