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. Author manuscript; available in PMC: 2022 Jul 20.
Published in final edited form as: Nature. 2022 Jun 15;606(7916):976–983. doi: 10.1038/s41586-022-04789-9

Fig. 2. Proposed aetiologies and prevalence of copy number signatures.

Fig. 2

A summary of the pan-cancer frequency, proposed aetiology (where possible), aetiology confidence rating, pattern of copy number change and distribution across cancer types is provided for each signature. Signatures are labelled based on pan-cancer prevalence, with signature CX1 having the highest pan-cancer frequency. Confidence measures for each signature aetiology are indicated by a star rating. The heatmap shows signature frequency for each of the 33 cancer types.