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. Author manuscript; available in PMC: 2022 Jul 23.
Published in final edited form as: Transplantation. 2019 Oct 1;103(10):2065–2074. doi: 10.1097/TP.0000000000002773

Figure 4. Interleukin-21 receptor (IL21R) blockade reduces human skin inflammation markers.

Figure 4

A, Immunohistochemistry for skin inflammation marker keratin 17 (Ker17). Typical example of the human skin graft of a vehicle-treated animal and an anti-IL-21R antibody (αIL-21R)-treated animal are depicted combined with the quantified data. B, Immunohistochemistry for proliferation marker Ki67. A typical example of the human skin graft of a vehicle-treated animal and an αIL-21R-treated animal are depicted combined with the quantified data. Quantified data are presented as mean proportions of the positive area with SEM. Magnification: ×10. Vehicle group n = 7, αIL-21R group n = 8 (*P < 0.05).