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. Author manuscript; available in PMC: 2022 Jul 23.
Published in final edited form as: Nature. 2021 Apr 26;593(7860):597–601. doi: 10.1038/s41586-021-03536-w

Extended Data Figure. 4. Differential expression analysis of AML cells after treatment with STM2457.

Extended Data Figure. 4

a) Volcano plot for MOLM13 cells treated with 1 µM STM2457 versus control samples after 48 hours of treatment, showing significantly dysregulated genes in red (Padj = 0.01). b) Extended gene ontology analysis of the differentially expressed genes post-treatment with 1 µM STM2457 in MOLM-13 cells. c) Representative GO signatures of the differentially expressed genes post-treatment with STM2457 in MOLM-13 cells. LFC, Log Fold Change.