Fig. 3. Early presymptomatic viral clearance is associated with activation of IL-17 signaling.

DEGs were determined by RNA-seq of nasal curettage samples at 3 dpi relative to baseline (7 to 14 days before inoculation) in the No Cold (n = 16) and Cold (n = 16) groups. Heatmaps show (A) DEGs in the No Cold group (n = 87) and (B) DEGs in the Cold group (n = 77). (C) Venn diagram of the number of overlapping DEGs in the Cold and No Cold groups. DEGs from the No Cold group were analyzed for enrichment of (D) GO molecular functions and (E) KEGG pathways. DEGs were defined as transcripts with P_adj < 0.01 and log² fold change >0.5.