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. 2022 Jun 20;14(8):905–913. doi: 10.1038/s41557-022-00972-7

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Extended Data Fig. 1 — Photo-cleavage reaction by the example of 5c (a). Illustration of the decrease of caged guanosine (G) after irradiation with 365 nm (b), 405 nm (c) or 420 nm (d) and the decrease of FlashCaps after irradiation with 365 nm (e), 405 nm (f) or 420 nm (g) for various periods of time. The samples (500 µM) were analysed via HPLC after irradiation via LED (365 nm (142 mW/cm²), 405 nm (142 mW/cm²); 420 nm (60 mW/cm²)). The percentage of uncaged guanosine or FlashCap was calculated by integration of the resulting peaks. Data points and error bars denote mean values ± standard deviation for n = 3 independent replicates.

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