Table 2. Parasitological and clinical effects of Trypanosoma brucei rhodesiense strains on mouse.

Parasitological and Clinical Parameters	Control	KETRI 3801	KETRI 2636	EATRO 1762	KETRI 3928
Median pre-patent period (IQR)	N/A	3(3–3)	4(3–5)	3(3–4)	4.5(4–8)^a
^✣First peak parasitaemia (dpi)	N/A	4	6	6	20
^†Clinical signs (days)	N/A	7	8	9	33
% PCV change at day 14 dpi	−2.42	−26.51	−25.48	−20.70	−3.68
% PCV change before extremis	−4.09 (56)	−26.51 (14)	−23.95 (28)	−17.58 (35)	−22.43 (56)
% Weight change	16.21	−24.12	−19.75	−17.79	13.84
^⨤Median survival time (days)	N/A	20	33	35	-

IQR: interquartile range.

dpi: days post infection.

^✣

First peak parasitaemia considered at level of ≥ antilog 7, and more often followed by reduction in parasite numbers.

^†

Clinical signs observed include rough or poor coat condition and pallor of skin, reduced activity, hunched appearance, laboured breathing and crowding.

^⨤

The values are estimated from Fig. 3.

Of the 10 mice, the pre-patent period of one animal was 17 days, and clearly an outlier.