. Author manuscript; available in PMC: 2022 Sep 7.

Published in final edited form as: Am J Respir Crit Care Med. 2018 Oct 15;198(8):1043–1054. doi: 10.1164/rccm.201801-0064OC

Table 1. Systemic Hemodynamic Variables at Baseline and throughout the Experimental Period in Fluid-resuscitated and Non−Fluid-resuscitated Animals.

	Mean Arterial Pressure (mm Hg) (Mean ± SD)			Cardiac Index (L/min/m²) (Median and IQR)			Systemic Vascular Resistance Index (dyn · s/cm⁵) (Median and IQR)
Time Point	FR Group (n = 8)	NR Group (n = 8)	P Value	FR Group (n = 8)	NR Group (n = 8)	P Value	FR Group (n = 8)	NR Group (n = 8)	P Value
TO, baseline, start endotoxin infusion	87.1 + 8.4	84.5 + 15.3	0.68	2.78 (2.61−3.18)	3.23 (2.78−3.74)	0.29	2,270 (1,918−2,815)	2,000 (1,757−2,111)	0.21
T3, start resuscitation	44.6 ± 9.4	48.5 ± 9.7	0.43	3.42 (2.52−3.72)	2.91 (2.70−3.04)	0.41	1,110 (950−1,230)	1,155 (1,029−1,340)	0.53
T4, end resuscitation/endotoxin	52.8 + 4.4	60.4 + 2.3	<0.001^*	4.94 (3.91−5.62)	3.08 (2.94−3.70)	0.006^*	714 (630−807)	1,434 (1,146−1,492)	<0.001^*
T6, 2 h after resuscitation	—	—	—	3.52 (3.08−3.96)	2.53 (2.27−3.28)	0.046^*	1,236 (1,043−1,379)	1,858 (1,425−2,176)	0.02^*
T8, 4 h after resuscitation	60.1 + 2.6	57.8 + 4.2	0.20	3.62 (2.92−4.28)	2.98 (2.59−3.66)	0.40	1,212 (982−1,372)	1,518 (1,248−1,722)	0.09
T12, 8 h after resuscitation	—	—	—	4.17 (3.62−4.98)	3.10 (2.76−4.71)	0.21	1,006 (871−1,149)	1,412 (806−1,513)	0.21
T16, 12 h after resuscitation	56.9 ± 3.4	61.9 ± 2.4	0.15	4.02 (3.14−5.26)	3.85 (3.47−5.53)	0.99	910 (814−1,036)	1,147 (827−1,269)	0.25

Definition of abbreviations: FR = fluid-resuscitated; IQR = Interquartile range; NR = non−fluid-resuscitated.

Statistically significant difference, P value < 0.05.