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. Author manuscript; available in PMC: 2022 Sep 5.
Published in final edited form as: Lancet Glob Health. 2020 Jan 1;8(1):e92–e100. doi: 10.1016/S2214-109X(19)30453-X

Table 1. Summary of included studies for the quantitative analysis.

Study design Country Inadvertent treatment Concomitant albendazole Gestational period Spontaneous abortions and stillbirths Congenital anomalies
Ivermectin-exposed group Control group Ivermectin-exposed group Control group
Chippaux et al (1993)32 Retrospective case-control study Cameroon Yes, during MDA programme No First trimester* 21/111 53/404 0/111 2/404
Doumbo et al (1992)33 Retrospective case-control study Mali Yes, during MDA programme No Unclear 3/82 6/139 0/82 1/139
Gyapong et al (2003)34 Retrospective case-control study Ghana Yes, during MDA programme Yes Unclear 2/50 21/293 1/50 5/293
Makene et al (2003)35 Retrospective case-control study Tanzania Yes, during MDA programme Yes Unclear NA NA 6/54 4/63
Ndyomugyenyi et al (2008)36 Open-label randomised controlled trial Uganda No Yes Second and third trimester 4/399 7/438 1/399 1/438
Pacque et al (1990)13 Retrospective case-control study Liberia Yes, during MDA programme No Unclear 5/203 55/1767 5/203 21/1767

Data are n/N, unless otherwise specified. MDA=mass drug administration. NA=not available. *97 of 110 were exposed during the first trimester of pregnancy; the remaining 13 were not specified. These 110 exposures generated 111 pregnancy outcomes.