Skip to main content
. Author manuscript; available in PMC: 2022 Sep 6.
Published in final edited form as: J Neurol Sci. 2021 May 29;427:117515. doi: 10.1016/j.jns.2021.117515

Table 1. Existing epilepsy classification schemes.

Organization Name Year Salient features
ILAE ILAE 1981
  • Partial: simple, complex, secondary

  • Generalised: absence, myoclonic, clonic, tonic-clonic, tonic

    1985
  • Semiology: focal vs. generalised

  • Idiopathic: idiopathic vs. symptomatic

  • Epilepsies are syndromes

    1989
  • Localization-related epilepsies and syndromes, generalised epilepsies and syndromes, epilepsies and syndromes undetermined to be generalised or focal, and special syndromes

    1993 (proposed)
  • Location: Generalised, partial, multiple seizure types, and unclassified seizures

  • Risk factors: provoked, unprovoked seizure of unknown etiology, cryptogenic

    2001 (proposed)
  • Five axes: ictal phenomenology, seizure type, syndrome, etiology, impairment

    2006 (proposed)
  • Five axes: ictal phenomenology, seizure type, syndrome, etiology, impairment

  • Delineation of self-limited epilepsy syndromes

    2010 (proposed)
  • Focal replaced partial

  • Etiology; genetic, structural, metabolic, unknown

  • Constellations: electroclinical syndromes with specific combinations of semiological, radiological, or pathological findings

    2017
  • Focal: networks limited to one hemisphere

  • Generalised: engage both hemispheres but begin anywhere within generalised networks

  • Seizures of unknown onset: if more information required

  • Epilepsies sequentially classified by seizure type, epilepsy type, and epileptic syndromes

Other Semiology 1998
  • Semiology-based: auras, autonomic seizures, dialeptic seizures, motor seizures, special seizures

  Five dimensional 2005
  • Five dimensions: location of epileptogenic zone, seizure semiology, etiology, seizure frequency, related medical conditions

  4D-CS 2012
  • Four dimensions: semiology, location of epileptogenic zone, etiology, associated comorbidities

    2019
  • Epileptic paroxysmal events: semiology, location of epileptogenic zone, etiology of epilepsy, associated comorbidities

  • Non-epileptic paroxysmal events: organic or psychogenic

  IEC 2020
  • Headline, seizure type, epilepsy type, etiology, comorbidities / relevant individual preferences

Integrated Epilepsy Classification (IEC), International League Against Epilepsy (ILAE), four-dimensional classification scheme (4D-CS).