Fig. 2. Different interventions tested in RSV clinical trials worldwide.

The global map shows the distribution of all RSV vaccine and drug trials worldwide. The inset shows an expanded view of clinical trial sites in Scotland. Each dot on the global map represents a single clinical trial site and is color-coded according to the type of intervention tested. Dots are in translucent colors to prevent overlapping dots (depicting proximal trial sites) from obscuring each other. Blue dots represent biologicals (vaccines and monoclonal antibodies), red dots represent antiviral drugs, and yellow dots represent other study designs including observational studies. Clicking on the blue box connects to an interactive map (https://rsvclinicaltrials.org/interventions.html) where each clickable dot produces a popup box containing detailed information about a particular study site. Here, the popup box provides details of a clinical trial at a study site in Glasgow, UK, for evaluating the safety and efficacy of the antiviral drug suptavumab in preterm infants. Source data for this interactive map were downloaded from clinicaltrials.gov (in December 2019). The search term used in the “condition or disease” field was “Respiratory Syncytial Virus”. All clinical trials that fulfilled this search criterion were added to the source data file that was used to generate the maps.