Fig. 4. Status of RSV clinical trials worldwide.

The recruitment status of different RSV vaccine and drug clinical trials as of December 2019 is shown. Yellow dots indicate trials that were active but had not yet started recruitment as of December 2019; red dots indicate completed trials. Green dots indicate inactive trials that had not yet begun recruitment as of December 2019; blue dots indicate trials that were actively recruiting in December 2019. Gray, purple, and black dots indicate trials that were terminated, of unknown status, or were halted, respectively. Dots are plotted in translucent colors to prevent overlapping dots (depicting proximal trial sites) from obscuring each other. Clicking on the blue box connects to an interactive map (https://rsvclinicaltrials.org/status.html) where each clickable dot produces a popup box containing detailed information about a particular study site. Here, the popup box provides details of a trial that evaluated an anti-RSV monoclonal antibody (MEDI-524) in children with congenital heart disease conducted at a trial site in Leeds, UK. Source data for this interactive map were downloaded from clinicaltrials.gov (in December 2019). The search term used in the “condition or disease”field was “Respiratory Syncytial Virus”. All clinical trials that fulfilled this search criterion were added to the source data file that was used to generate the maps.