Figure 5. HR for CAD Riskin UK Biobank.
(A) Model is adjusted for sex. (B) Model is adjusted for sex and inverse-normal transformed lipoprotein(a) (Lp(a)) concentration. Plot is restricted to individuals with Lp(a) measurements available. Status refers to the presence (yes) or absence (no) of the proxy single nucleotide polymorphisms (SNPs) rs6938647/rs75692336 for 4733G>A/4925G>A. The noncarriers of proxy SNPs of both variants make up the reference group. Age is taken as time scale (model with time-on-study shown in Supplemental Figure 10). HR for Lp(a) concentration is given for a 1-unit increase of the inverse-normal transformed Lp(a) concentration. CAD = coronary artery disease.